EQUEST
contains unique active ingredient moxidectin – a second
generation macrocyclic lactone (ML). Different in molecular
structure and spectrum of activity compared to other macrocyclic
lactones including ivermectin.
• EQUEST has the longest dosing
interval of any routine wormer, with its 13-week dosing interval.
The unique persistency of EQUEST prevents
the re-appearance of worm eggs in the dung for at least 90
days, that’s longer than pyrantel, mebendazole, fenbendazole
and
ivermectin-based wormers (Jacobs
D et al, 1995) (Parr S et al), and gives EQUEST its
13-week dosing interval.
Just one single dose of EQUEST is required
a season for the routine control of roundworms, and it also
controls bots.
• EQUEST is the only wormer to control
all stages of encysted small redworm, that’s the inhibited
and developing stages with a SINGLE standard dose.
Over 90% of the small redworm in your
horse can be encysted in its gut wall. Undetectable, horses
can harbour tens of thousands of encysted small redworm with
no visible illness (Love S et al, 1999).
Killing these larvae before they emerge ‘en masse’
and cause potentially fatal intestinal damage is an important
part of any worm control programme.
Ivermectin, mebendazole and pyrantel-based
wormers are simply not effective against encysted small redworm,
and
fenbendazole-based wormers require a 5-day course. With
widespread small redworm resistance to fenbendazole, prevalent
on over 80% of stables in the UK (Fisher
M et al, 1992), and the fact that this 5-day course
actually may increase the selection pressure for resistance
amongst small redworm (Reinemeyer C
et al, 2003), the use of fenbendazole for the control
of encysted small redworm is not advisable where resistance
is present (Coles G et al, 2003).
• EQUEST is the only wormer to carry
on killing small redworm larvae ingested while your horse
grazes for a further two weeks after treatment, cleaning the
pasture of this parasite and reducing your horse’s exposure
to re-infection. |
|
 |
|
|
Larvae
ingested by your horse as it grazes invade and accumulate
in the horse’s gut wall. With warmer and wetter
winters the peak periods for larval infestation have
expanded resulting in the potential for larvae to be
picked up late in the year (Love
S, 2003). This accumulation of larvae during
the grazing season causes damage and inflammation to
the horse’s gut wall resulting in weight loss,
as well as having the potential to cause life-threatening
illness (Love S et al, 1999).
• EQUEST has no confirmed resistance in horses
in the UK or Ireland.
Resistance has been reported in small and large redworm
against pyrantel-based wormers (Coles
G et al, 1999) and there is widespread small
redworm resistance to benzimidazoles (Fisher
M et al, 1992) (i.e. fenbendazole and mebendazole).
In comparison EQUEST has no reported resistance in horses
in the UK or Ireland, and EQUEST is effective against
the increasingly prevalent benzimidazole-resistant small
redworms.
• EQUEST is kind to the environment.
With lower toxicity to dung dwelling insects than
ivermectin-based wormers (Herd
R, 1995), insects can carry on cleaning the pasture
of dung.
• EQUEST is trusted by thousands of horse owners
worldwide.
Millions of doses of EQUEST have been safely given
to horses of all kinds and research has shown it is
safe to use in pregnant and lactating mares, stallions
and foals over four months of age.
• AND finally EQUEST is now presented in a traditional
dial-a-dose syringe offering easier and more accurate
dosing.
The unique clear gel formula simply melts in
your horse’s mouth; and
so reduces the risk of being spat
out.
Advice on the use of this or alternative medicines must be sought from the medicine prescriber.
|
|
| |
| |
|
